Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 190
interventional 101
Observational 78
Registry 11

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Other 27
Procedure 18
Drug 12
Device 8
Drug|placebo 8
Behavioral 6
Diagnostic Test 6
Radiation 6
Other|Procedure 3
Behavioral|Other 2
Behavioral|Drug 1
Device|Other 1
Diagnostic Test|Other 1
Genetic 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 44
Netherlands 6
France 5
NA 5
Norway 5
United Kingdom 5
Canada 4
Denmark 4
Korea, Republic of 4
Turkey 3
Israel 2
Singapore 2
Sweden 2
Austria 1
Austria|Czechia|Denmark|Germany|Hungary|Ireland|Italy|Latvia|Lithuania|Poland|Portugal|Romania|Serbia|Spain|United Kingdom 1
Canada|Denmark|Germany|Netherlands|Norway|Sweden 1
Finland 1
Ireland|United Kingdom 1
Italy 1
Malaysia 1
Palestinian Territory, occupied 1
Spain 1
Tunisia 1

Sites per Study

Site_count Study_Count
1 83
2 7
3 2
4 2
5 1
9 1
10 1
16 1
17 1
20 1
79 1

Phase

Phase Study_Count
N/A 70
Phase 4 15
Phase 3 7
Phase 2 5
Phase 1 2
Early Phase 1 1
Phase 2/Phase 3 1

Number of Arms

Number_of_Arms Count_of_Studies
1 14
2 67
3 5
4 2
NA 13

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 115 10.0000 24.0 58.0 68 32.000 13.0000
1st Qu. 115 106.2500 26.5 66.0 68 70.750 49.5000
Median 115 212.5000 29.0 200.0 68 351.500 70.0000
Mean 115 526.2286 29.0 197.8 68 1598.167 273.0667
3rd Qu. 115 400.0000 31.5 305.0 68 745.500 118.0000
Max. 115 10003.0000 34.0 360.0 68 8000.000 1690.0000

Trial Group Type

group_type Group_Count
Experimental 62
Active Comparator 49
No Intervention 29
Other 18
NA 13
Placebo Comparator 11
Sham Comparator 2

Intervention Model

intervention_model Study_Count
Parallel Assignment 71
Single Group Assignment 19
Crossover Assignment 5
NA 4
Factorial Assignment 2

Primary Purpose

primary_purpose Study_Count
Diagnostic 49
Treatment 32
Other 7
Health Services Research 4
Prevention 4
Supportive Care 2
Basic Science 1
Screening 1
NA 1

Observational Studies

Studies by Country

Country Study_Count
United States 36
NA 8
France 5
United Kingdom 4
Germany 3
China 2
Denmark 2
Israel 2
Netherlands 2
Norway 2
Singapore 2
Switzerland 2
Argentina|Norway 1
Belgium 1
Belgium|France 1
Canada 1
Italy 1
Spain 1
Sweden 1
United States|Israel 1

Sites per Study

Site_count Study_Count
1 56
2 5
3 2
4 2
5 1
6 2
7 3
10 2
11 1
12 1
13 2
50 1

Enrollment Metrics

Measure Observational
Min 1.000
1st Qu 105.500
Median 383.500
Mean 2631.051
3rd Qu 1375.250
Max 42926.000

Observation Model

observational_model Study_Count
Cohort 58
Case-Only 8
Case-Control 3
Case Control 3
Other 3
NA 3

Time Perspective

time_perspective Study_Count
Prospective 66
Retrospective 8
NA 2
Cross-Sectional 1
Other 1

Registries

Studies by Country

Country Study_Count
Germany 3
China 2
Brazil 1
Denmark 1
Israel 1
Sweden 1
United Kingdom 1
United States 1

Sites per Study

Site_count Study_Count
1 6
2 2
3 1
6 1
9 1

Enrollment Metrics

Measure Registries
Min 100.000
1st Qu 1050.000
Median 2000.000
Mean 3315.727
3rd Qu 4198.000
Max 10000.000

Registry Model

observational_model Study_Count
Cohort 11

Time Perspective

time_perspective Study_Count
Prospective 11

Follow-up

target_duration Study_Count
1 Year 2
30 Days 2
1 Day 1
1 Month 1
12 Months 1
123 Months 1
3 Months 1
4 Years 1
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03365375 Mindfulness-Based Stress Reduction for Adults With Low-Risk Chest Pain Associated With Anxiety https://ClinicalTrials.gov/show/NCT03365375 Recruiting Indiana University 2019-07-01
NCT03929341 Risk Evaluation and Stratification of Low Risk for Cardiovascular Disease in Women https://ClinicalTrials.gov/show/NCT03929341 Recruiting Women’s College Hospital 2021-01-31
NCT03336112 Internet-delivered CBT for Patients With NCCP https://ClinicalTrials.gov/show/NCT03336112 Recruiting Linkoeping University 2020-12-31
NCT03319121 The Evaluation of Effectiveness Between Empirical and Guided Therapy for Unexplained Non-Cardiac Chest Pain https://ClinicalTrials.gov/show/NCT03319121 Completed Universiti Sains Malaysia 2017-12-31
NCT03187639 Fractional Flow Reserve Derived From Computed Tomography Coronary Angiography in the Assessment and Management of Stable Chest Pain https://ClinicalTrials.gov/show/NCT03187639 Active, not recruiting University Hospital Southampton NHS Foundation Trust 2020-06-01
NCT03120351 Lidocaine 5% Patch (Lidoderm) for the Prevention of Acute and Chest Pain Following Robotic Valve Surgery https://ClinicalTrials.gov/show/NCT03120351 Completed The Cleveland Clinic 2011-04-30
NCT03096925 Non-cardiac Chest Pain: Effect of Cognitive Therapy Administered as Guided Self-help https://ClinicalTrials.gov/show/NCT03096925 Active, not recruiting Sorlandet Hospital HF 2019-12-19
NCT03058120 Henry Ford Heart Score Randomized Trial: Rapid Discharge of Patients Evaluated for Possible Myocardial Infarction https://ClinicalTrials.gov/show/NCT03058120 Completed Henry Ford Health System 2015-05-08
NCT02947360 The FOVUS-ER Study: Focused Vascular Ultrasound to Risk Stratify Patients With Chest Pain in the ER https://ClinicalTrials.gov/show/NCT02947360 Completed Queen’s University 2018-12-17
NCT02914834 Acupuncture for Individuals With Stable Angina https://ClinicalTrials.gov/show/NCT02914834 Recruiting University of Illinois at Chicago 2021-03-01
NCT02905383 The Effect of Exercise on Physical Function and Health in Older People After Discharge From Hospital https://ClinicalTrials.gov/show/NCT02905383 Active, not recruiting Oslo Metropolitan University 2020-05-31
NCT02892903 In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes? https://ClinicalTrials.gov/show/NCT02892903 Active, not recruiting University Hospital Southampton NHS Foundation Trust 2019-12-31
NCT02861508 Impact of Immediate Point-of-Care Ultrasound on Patients With Cardiopulmonary Symptoms in the Emergency Department https://ClinicalTrials.gov/show/NCT02861508 Completed Yale University 2018-06-30
NCT02617888 Effects of Heart Imaging Radiation on DNA Double-Stranded Breaks in Blood Lymphocytes and Hair Follicle Cells https://ClinicalTrials.gov/show/NCT02617888 Completed Walter Reed National Military Medical Center 2015-09-30
NCT02608255 A Prospective Pilot Study to Evaluate a New Marker of Ischemia in Chest Pain Triage https://ClinicalTrials.gov/show/NCT02608255 Completed Assistance Publique Hopitaux De Marseille 2016-11-30
NCT03400579 A Study of the Feasibility of Prehospital Remote Ischemic Conditioning https://ClinicalTrials.gov/show/NCT03400579 Completed University of North Carolina, Chapel Hill 2019-09-30
NCT02538861 Acute Chest Pain Imaging in the ED With the Combine CCTA and CT Perfusion https://ClinicalTrials.gov/show/NCT02538861 Active, not recruiting Baptist Health South Florida 2020-12-31
NCT02538770 Rapid Viral Diagnostics in Adults to Reduce Antimicrobial Consumption and Duration of Hospitalization https://ClinicalTrials.gov/show/NCT02538770 Completed University of Oulu 2015-11-30
NCT02469610 Assessment of Intercostal Block Scheduling in Preventing Acute Surgical and Post-surgical Pain in Thoracoscopic Surgery https://ClinicalTrials.gov/show/NCT02469610 Completed Carmel Medical Center 2017-01-30
NCT02400229 Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease https://ClinicalTrials.gov/show/NCT02400229 Active, not recruiting Charite University, Berlin, Germany 2020-04-30
NCT02373527 Can we Safely Have Our Patients Eat With Cardiac Catheterization - Nix Or alloW: The CHOW NOW Study https://ClinicalTrials.gov/show/NCT02373527 Completed The Guthrie Clinic 2019-04-12
NCT02346565 Stress Echocardiography Versus Exercise ECG (ExECG) in Women With Chest Pain https://ClinicalTrials.gov/show/NCT02346565 Active, not recruiting London North West Healthcare NHS Trust 2020-12-31
NCT02336880 Internet-delivered CBT for NCCP-patients - a Pilot Trial https://ClinicalTrials.gov/show/NCT02336880 Completed Linkoeping University 2015-03-31
NCT02144090 Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study https://ClinicalTrials.gov/show/NCT02144090 Completed Laval University 2015-05-31
NCT01293019 Osteopathic Treatment in Adult Patients With Cystic Fibrosis https://ClinicalTrials.gov/show/NCT01293019 Completed Assistance Publique - Hôpitaux de Paris 2011-04-30
NCT02031016 Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain https://ClinicalTrials.gov/show/NCT02031016 Completed St. Antonius Hospital 2016-04-30
NCT01969916 Stress CT Perfusion in Patients With Chest Pain https://ClinicalTrials.gov/show/NCT01969916 Completed University of Chicago 2018-06-30
NCT01969240 Shared Decision Making in the Emergency Department: Chest Pain Choice Trial https://ClinicalTrials.gov/show/NCT01969240 Completed Mayo Clinic 2015-08-31
NCT01931852 Cardiac Magnetic Resonance Imaging Strategy for the Management of Patients With Acute Chest Pain and Detectable to Elevated Troponin https://ClinicalTrials.gov/show/NCT01931852 Active, not recruiting Wake Forest University Health Sciences 2021-03-31
NCT01927640 Dexmedetomidine for Reversal of Cocaine’s Effects on the Heart https://ClinicalTrials.gov/show/NCT01927640 Completed Cedars-Sinai Medical Center 2014-01-15
NCT01770444 Low-Dose Coronary Computed Tomographic Angiography for Early Triage of Acute Chest Pain https://ClinicalTrials.gov/show/NCT01770444 Completed Seoul National University Hospital 2016-04-30
NCT01756846 Impact on Management of the HEART Risk Score in Chest Pain Patients https://ClinicalTrials.gov/show/NCT01756846 Completed UMC Utrecht 2014-10-31
NCT01665521 Efficacy Evaluation of the HEART Pathway in Emergency Department Patients With Acute Chest Pain https://ClinicalTrials.gov/show/NCT01665521 Completed Wake Forest University Health Sciences 2016-02-20
NCT01604655 ProspEctive First Evaluation in Chest Pain Trial https://ClinicalTrials.gov/show/NCT01604655 Completed St. Luke’s-Roosevelt Hospital Center 2013-12-31
NCT01598207 The Effects of Cannabinoid on Patients With Non-GERD Related Non Cardiac Chest Pain https://ClinicalTrials.gov/show/NCT01598207 Completed University of Iowa 2014-05-31
NCT01582165 Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance https://ClinicalTrials.gov/show/NCT01582165 Completed Oslo University Hospital 2016-06-30
NCT01572220 Stress Echo Ultrasound Contrast in an Urban Safety Net Hospital to Refine Ischemia Evaluation https://ClinicalTrials.gov/show/NCT01572220 Completed Denver Health and Hospital Authority 2014-08-31
NCT01559467 The Supplementary Role of Non-invasive Imaging to Routine Clinical Practice in Suspected Non-ST-elevation Myocardial Infarction https://ClinicalTrials.gov/show/NCT01559467 Completed Maastricht University Medical Center 2017-05-31
NCT01534000 Cardiac-CT in the Treatment of Acute Chest Pain https://ClinicalTrials.gov/show/NCT01534000 Completed Hvidovre University Hospital 2014-01-31
NCT01486394 Sonography in an Unselected Population of Acute Admitted Patients With Respiratory Symptoms https://ClinicalTrials.gov/show/NCT01486394 Completed Odense University Hospital 2013-04-30
NCT01413282 Better Evaluation of Acute Chest Pain With Computed Tomography Angiography https://ClinicalTrials.gov/show/NCT01413282 Completed Erasmus Medical Center 2014-02-28
NCT01384448 Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain https://ClinicalTrials.gov/show/NCT01384448 Completed Montefiore Medical Center 2016-02-29
NCT01345188 Ranolazine in Ischemic Cardiomyopathy https://ClinicalTrials.gov/show/NCT01345188 Completed Midwest Cardiovascular Research Foundation 2014-04-30
NCT01334645 Copeptin and Acute Coronary Syndrome Without ST-segment Elevation https://ClinicalTrials.gov/show/NCT01334645 Completed University Hospital, Clermont-Ferrand 2012-03-31
NCT01328795 Cardiogoniometry (CGM) for Early Diagnosis of Acute Coronary Syndromes (ACS) https://ClinicalTrials.gov/show/NCT01328795 Completed Stiftung Institut fuer Herzinfarktforschung 2010-04-30
NCT04429698 The Effects of Point-of-care Ultrasonography https://ClinicalTrials.gov/show/NCT04429698 Completed Sakarya University 2019-01-15
NCT04393909 Improving Safety of Diagnosis and Therapy in the Inpatient Setting https://ClinicalTrials.gov/show/NCT04393909 Recruiting Brigham and Women’s Hospital 2021-06-30
NCT00468325 Coronary Computed Tomography for Systematic Triage of Acute Chest Pain Patients to Treatment (CT-STAT) https://ClinicalTrials.gov/show/NCT00468325 Completed William Beaumont Hospitals 2008-11-30
NCT04114760 Timely Acquirement of 12-lead ECG Using Patchy-type Wireless Device by Emergency Medical Technician in Ambulance https://ClinicalTrials.gov/show/NCT04114760 Enrolling by invitation Samsung Medical Center 2020-02-28
NCT04094532 Transversus Thoracic Muscle Plane Block for Open Heart Surgery https://ClinicalTrials.gov/show/NCT04094532 Completed Ataturk University 2020-01-01
NCT04048733 Timely Acquirement of 12-lead ECG Using Patchy-type Wireless Device Among Patient With Chest Pain https://ClinicalTrials.gov/show/NCT04048733 Recruiting Samsung Medical Center 2019-12-11
NCT03952351 Troponin in Acute Chest Pain to Risk Stratify and Guide EffecTive Use of Computed Tomography Coronary Angiography https://ClinicalTrials.gov/show/NCT03952351 Recruiting University of Edinburgh 2023-11-30
NCT03781661 Providing Patient Information and CT Examination Results https://ClinicalTrials.gov/show/NCT03781661 Active, not recruiting Haukeland University Hospital 2019-03-04
NCT03770208 RIB PAIN (Rib Fractures Treated With Parental Analgesia With Infused LidocaiNe) https://ClinicalTrials.gov/show/NCT03770208 Recruiting Western University, Canada 2019-12-31
NCT03674021 Use of Visual Decision Aid for Shared Decision Making in Chest Pain https://ClinicalTrials.gov/show/NCT03674021 Recruiting National University Hospital, Singapore 2021-03-01
NCT03664973 Serratus Plane Block for Rib Fractures https://ClinicalTrials.gov/show/NCT03664973 Recruiting Arcispedale Santa Maria Nuova-IRCCS 2019-09-30
NCT03486340 Prevention of Chest Pain in Chemo-treated Cancer Patients https://ClinicalTrials.gov/show/NCT03486340 Recruiting Vejle Hospital 2021-12-31
NCT03426436 Evaluation of Synthesized 18-Lead ECG in the Emergency Department https://ClinicalTrials.gov/show/NCT03426436 Completed Nihon Kohden 2018-08-16
NCT01174550 PROspective Multicenter Imaging Study for Evaluation of Chest Pain https://ClinicalTrials.gov/show/NCT01174550 Completed Duke University 2014-10-31
NCT01135095 Low Dose One-Day Tc99m Protocol With a High-Efficiency Cardiac Dedicated Gamma Camera For Detection of Coronary Disease https://ClinicalTrials.gov/show/NCT01135095 Completed Spectrum Dynamics 2012-06-30
NCT01114100 The Effects of Treatment With Sertraline for Noncardiac Chest Pain https://ClinicalTrials.gov/show/NCT01114100 Completed Maastricht University Medical Center 2002-12-31
NCT01077037 Impact of a Decision Aid on Patient Decision Making in Emergency Department Chest Pain Patients https://ClinicalTrials.gov/show/NCT01077037 Completed Mayo Clinic 2011-02-28
NCT01070771 Does Routine Pressure Wire Assessment Influence Management Strategy at Coronary Angiography for Diagnosis of Chest Pain? https://ClinicalTrials.gov/show/NCT01070771 Completed University Hospital Southampton NHS Foundation Trust 2012-08-31
NCT01067456 Comprehensive Cardiothoracic Dual Source CT for the Early Triage of Patients With Acute Chest Pain https://ClinicalTrials.gov/show/NCT01067456 Completed Massachusetts General Hospital 2009-06-30
NCT01035047 Randomized Investigation of Chest Pain Diagnostic Strategies https://ClinicalTrials.gov/show/NCT01035047 Completed Wake Forest University Health Sciences 2011-10-31
NCT00960245 Relative Bioavailability Study of Nadolol (1 x 80 mg) Tablets Under Fasting Conditions https://ClinicalTrials.gov/show/NCT00960245 Completed Sandoz 1994-07-31
NCT00869245 Efficacy Evaluation of Observation Unit Cardiac Magnetic Resonance Imaging (MRI) in Patients With Intermediate Risk Acute Chest Pain https://ClinicalTrials.gov/show/NCT00869245 Completed Wake Forest University Health Sciences 2010-09-30
NCT00846469 Coronary Computed Tomography (CT) Angiography Versus Standard Therapy in the Emergency Room https://ClinicalTrials.gov/show/NCT00846469 Completed University of Michigan 2012-06-30
NCT03583320 Trial of Cardiac CT in Acute Chest Patients With Intermediate Level Initial High-sensitivity Cardiac Troponin https://ClinicalTrials.gov/show/NCT03583320 Active, not recruiting Guy’s and St Thomas’ NHS Foundation Trust 2019-04-05
NCT00825435 Coronary CT Angiography in Acute Chest Pain is a Cost Effective Risk Stratification Strategy https://ClinicalTrials.gov/show/NCT00825435 Completed University of Texas Southwestern Medical Center 2012-09-30
NCT04125992 Distal Radial Artery vs. Forearm Radial Artery For Cardiac Catheterization https://ClinicalTrials.gov/show/NCT04125992 Recruiting An-Najah National University 2020-01-31
NCT03129659 Coronary CT Angiography for Improved Assessment of Suspected Acute Coronary Syndrome https://ClinicalTrials.gov/show/NCT03129659 Recruiting Erasmus Medical Center 2020-09-01
NCT03922516 Accuracy of Ultra-Low-Dose-CT of the Chest Compared to Plain Film in an Unfiltered Emergency Department Patient Cohort https://ClinicalTrials.gov/show/NCT03922516 Completed Medical University of Vienna 2019-11-26
NCT03164226 The Evaluation of Endothelial Function in the Diagnosis of Acute Coronary Syndrome (ACS) https://ClinicalTrials.gov/show/NCT03164226 Recruiting University of Monastir 2040-05-15
NCT00769574 Assessment of New Biomarkers in the Management and Triage of Patients With Chest Pain and Suspicion of Non ST Elevation Acute Coronary Syndrome. https://ClinicalTrials.gov/show/NCT00769574 Completed Assistance Publique Hopitaux De Marseille 2011-08-31
NCT00709670 ComParative Diagnostic Study Between Multislice Computed Tomography (MSCT) and Stress Echography in Coronarin Patients. https://ClinicalTrials.gov/show/NCT00709670 Completed Assistance Publique - Hôpitaux de Paris 2011-09-30
NCT00705458 Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Chest Pain https://ClinicalTrials.gov/show/NCT00705458 Completed Montefiore Medical Center 2013-03-31
NCT00678639 Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain https://ClinicalTrials.gov/show/NCT00678639 Completed Wake Forest University Health Sciences 2009-03-31
NCT00674375 Risk Score Alerts for Chest Pain Care https://ClinicalTrials.gov/show/NCT00674375 Completed Harvard Vanguard Medical Associates 2010-01-31
NCT00800527 Efficacy of Gabapentin in the Treatment of Chest Pain and Paresthesia in Patients With Sternotomy https://ClinicalTrials.gov/show/NCT00800527 Completed Usak State Hospital 2008-06-30
NCT00644657 The Effect of Clopidogrel on Coated-Platelets in Patients Undergoing Cardiac Catheterization https://ClinicalTrials.gov/show/NCT00644657 Completed University of Oklahoma 2008-09-30
NCT00623454 Non Cardiac Chest Pain and Benign Palpitations https://ClinicalTrials.gov/show/NCT00623454 Completed Norwegian University of Science and Technology 2009-04-30
NCT00623207 Use of Atropine in Tredmill Stress Testing https://ClinicalTrials.gov/show/NCT00623207 Completed HaEmek Medical Center, Israel 2009-10-31
NCT00614354 Study of 99mTc-glucarate to Detect Acute Coronary Syndrome in Chest Pain Patients. https://ClinicalTrials.gov/show/NCT00614354 Completed Molecular Targeting Technologies, Inc. 2010-09-30
NCT00536224 Chest Pain Observation Unit Risk Reduction Trial https://ClinicalTrials.gov/show/NCT00536224 Completed University of Iowa 2009-07-31
NCT00493844 N-terminal Pro B-type Natriuretic Peptide (Nt-proBNP) Versus Exercise Test for Evaluation of Acute Chest Pain https://ClinicalTrials.gov/show/NCT00493844 Completed University of Valencia 2008-06-30
NCT00476398 Evaluation of Patients With Non-cardiac Chest Pain https://ClinicalTrials.gov/show/NCT00476398 Completed Brigham and Women’s Hospital 2009-06-30
NCT00462241 Treatment Study Comparing Manual Treatment or Advice in Acute, Musculoskeletal Chest Pain https://ClinicalTrials.gov/show/NCT00462241 Completed Clinical Locomotion Science 2008-03-31
NCT00434564 Acute Chest Pain Treatment and Evaluation (ACTION) Study https://ClinicalTrials.gov/show/NCT00434564 Completed Singapore General Hospital NA
NCT00431886 Usefulness of 64 Slice Multi-Detector Computed Tomography as a First Diagnostic Approach in Acute Chest Pain Patients https://ClinicalTrials.gov/show/NCT00431886 Completed Seoul National University Bundang Hospital NA
NCT00348569 A Study of Computed Tomography (CT) for Evaluation of Coronary Artery Blockages in Typical or Atypical Chest Pain https://ClinicalTrials.gov/show/NCT00348569 Completed GE Healthcare 2007-01-31
NCT00273832 Study of Coronary Artery Computed Tomography to Diagnose Emergency Chest Pain https://ClinicalTrials.gov/show/NCT00273832 Completed William Beaumont Hospitals NA
NCT00251901 Chest Pain Pilot Study https://ClinicalTrials.gov/show/NCT00251901 Completed AstraZeneca 2005-07-31
NCT00219674 At-Home Automated External Defibrillator (AED) Training Study https://ClinicalTrials.gov/show/NCT00219674 Completed Public Health - Seattle and King County 2009-03-31
NCT00187889 EWISE: Study of Eplerenone in Women With Chest Pain, Coronary Vascular Dysfunction and Evidence of Myocardial Ischemia https://ClinicalTrials.gov/show/NCT00187889 Completed University of Florida 2009-02-28
NCT00150826 QWISE - Study of Quinapril in Women With Chest Pain, Coronary Flow Reserve Limitations and Evidence of Myocardial Ischemia https://ClinicalTrials.gov/show/NCT00150826 Completed University of Florida 2004-12-31
NCT00081913 Stem Cell Study for Patients With Heart Disease https://ClinicalTrials.gov/show/NCT00081913 Completed Losordo, Douglas, M.D. 2006-03-31
NCT00075088 Tele-Electrocardiography in Emergency Cardiac Care https://ClinicalTrials.gov/show/NCT00075088 Completed University of California, San Francisco 2009-06-30
NCT00005575 Treatment of Non-Cardiac Chest Pain With Imipramine or Cognitive-Behavioral Therapy https://ClinicalTrials.gov/show/NCT00005575 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NA
NCT00001961 MRI Evaluation of Chest Pain https://ClinicalTrials.gov/show/NCT00001961 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001716 Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia https://ClinicalTrials.gov/show/NCT00001716 Completed National Institutes of Health Clinical Center (CC) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04458155 Li-Hep vs. Non-Li-Hep Coated Transfer Device https://ClinicalTrials.gov/show/NCT04458155 Recruiting VieCuri Medical Centre 2021-01-01
NCT02984436 High-Sensitivity Cardiac Troponin T to OPtimize Chest Pain Risk Stratification https://ClinicalTrials.gov/show/NCT02984436 Active, not recruiting University of Florida 2019-12-31
NCT03329469 The Value of CT-FFR Compared to CCTA or CCTA and Stress MPI in Low to Intermediate Risk ED Patients With Toshiba CT-FFR https://ClinicalTrials.gov/show/NCT03329469 Enrolling by invitation Northwell Health 2020-12-31
NCT03286179 Standardizing Emergency Work-ups Around Risk Data https://ClinicalTrials.gov/show/NCT03286179 Active, not recruiting Kaiser Permanente 2019-12-31
NCT03255772 Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients https://ClinicalTrials.gov/show/NCT03255772 Completed Genetesis Inc. 2017-12-30
NCT03227159 Study for Evaluation of Newly Onset Chest Pain and Rapid Diagnosis of Myocardial Necrosis https://ClinicalTrials.gov/show/NCT03227159 Completed Universitätsklinikum Hamburg-Eppendorf 2008-12-31
NCT03217227 Evaluating Myocardial Ischemia in Chest Pain Using Exercise CMR https://ClinicalTrials.gov/show/NCT03217227 Recruiting National Heart Centre Singapore 2021-03-01
NCT03026283 The Value of CT Fractional Flow Reserve https://ClinicalTrials.gov/show/NCT03026283 Completed Northwell Health 2018-06-30
NCT02983812 Developing Enhanced Prediction Models https://ClinicalTrials.gov/show/NCT02983812 Completed University of Pennsylvania 2019-06-07
NCT02897492 Rapid and Highly Sensitive Detection of Fluorescently-labeled Troponin in Patients Admitted With Chest Pain https://ClinicalTrials.gov/show/NCT02897492 Completed Rambam Health Care Campus 2019-03-01
NCT02813499 Interest of CARE Rule to Exclude the Hypothesis of an Acute Coronary Syndrome Without Bioassay - ICARE https://ClinicalTrials.gov/show/NCT02813499 Completed University Hospital, Angers 2018-01-31
NCT02789904 Evaluation of hsTnI in the Management of Patients With Chest Pain in the Emergency Department https://ClinicalTrials.gov/show/NCT02789904 Active, not recruiting National Heart Centre Singapore 2022-11-30
NCT02719509 Emergency Department Cardiac Ultrasound https://ClinicalTrials.gov/show/NCT02719509 Completed Hennepin Healthcare Research Institute 2016-06-30
NCT02709135 PARA-HEART Pilot Implementation https://ClinicalTrials.gov/show/NCT02709135 Completed Wake Forest University Health Sciences 2018-08-30
NCT02620202 Aiming Towards Evidence Based Interpretation of Cardiac Biomarkers in Patients Presenting With Chest Pain https://ClinicalTrials.gov/show/NCT02620202 Recruiting Haukeland University Hospital 2020-04-30
NCT02581540 Mersey Acute Coronary Syndrome Rule-Out Using High Sensitive Troponin https://ClinicalTrials.gov/show/NCT02581540 Completed Liverpool University Hospitals NHS Foundation Trust 2016-07-31
NCT04153006 Comparison of Fingerstick Versus Venous Sample for Troponin I. https://ClinicalTrials.gov/show/NCT04153006 Active, not recruiting VieCuri Medical Centre 2020-03-13
NCT02575768 Myocardial Flow Reserve in Severe AS Without Obstructive Coronary Artery Disease https://ClinicalTrials.gov/show/NCT02575768 Completed Samsung Medical Center 2015-04-30
NCT02440893 Understanding the Effect of Metformin on Corus CAD (or ASGES) https://ClinicalTrials.gov/show/NCT02440893 Completed CardioDx 2014-06-30
NCT02405754 Clinical Utility of an Age, Sex, and Gene Expression Score (ASGES or Corus CAD) in African American Patients. https://ClinicalTrials.gov/show/NCT02405754 Completed CardioDx 2014-04-30
NCT02364271 Early Risk Stratification in ED Chest Pain Patients https://ClinicalTrials.gov/show/NCT02364271 Completed Chinese University of Hong Kong 2014-10-31
NCT02359773 Magnetocardiography as a Tool for Patients Presenting With Chest Pain - Pilot Study https://ClinicalTrials.gov/show/NCT02359773 Completed Quantum Imaging Limited 2015-07-31
NCT02223286 Understanding Clinician Utilization of Corus CAD (Age/Sex/Gene Expression Score - ASGES) in Clinical Decision Making https://ClinicalTrials.gov/show/NCT02223286 Completed CardioDx 2014-06-30
NCT02107001 Lung Ultrasound in Pleuritic Chest Pain https://ClinicalTrials.gov/show/NCT02107001 Completed University of Milan 2015-11-30
NCT02056964 HEART Pathway Implementation https://ClinicalTrials.gov/show/NCT02056964 Completed Wake Forest University Health Sciences 2019-01-31
NCT02055443 Myocardial Ischemia Detection for Early Identification of Patients With Ischemic Chest Pain https://ClinicalTrials.gov/show/NCT02055443 Completed University of Pittsburgh 2016-12-31
NCT02042209 Medical Telephone Triage of Emergency Calls for Thoracic Pain https://ClinicalTrials.gov/show/NCT02042209 Completed University Hospital, Toulouse 2011-12-31
NCT02015858 Pain During Chest Tube Withdrawal: Evaluation Using Pan Monitor https://ClinicalTrials.gov/show/NCT02015858 Completed Hopital Foch 2014-05-31
NCT01953276 Are Serial Electrocardiograms Additive to SeriAl Second-generations Troponins in Predicting Acute CoronAry Syndromes in PatienTs With Undifferentiated cHest Pain https://ClinicalTrials.gov/show/NCT01953276 Completed Wake Forest University Health Sciences 2015-05-31
NCT01890525 PROMISE Substudy to Assess For Effective Dose of Radiation (PROMISE-SAFER) Specific Aim 3b https://ClinicalTrials.gov/show/NCT01890525 Completed Kaiser Permanente 2016-08-15
NCT01839058 Is Non-Cardiac Chest Pain Caused by Sustained Longitudinal Smooth Muscle Contraction? https://ClinicalTrials.gov/show/NCT01839058 Completed Queen’s University 2014-10-31
NCT01724996 Usefulness of Chest Wall Tenderness as Bedside Test to Exclude Acute Coronary Syndrome in Different Demographic Groups https://ClinicalTrials.gov/show/NCT01724996 Completed University of Zurich 2013-11-30
NCT01715376 Effects of Integrated Treatment by Traditional Chinese and Western Medicine in Reducing Cardiovascular Events https://ClinicalTrials.gov/show/NCT01715376 Completed Changchun University of Chinese Medicine 2013-09-30
NCT01677156 A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (or ASGES) in Primary Care Settings https://ClinicalTrials.gov/show/NCT01677156 Completed CardioDx 2014-09-30
NCT01618123 Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit https://ClinicalTrials.gov/show/NCT01618123 Active, not recruiting Sheba Medical Center 2020-12-31
NCT01594411 PCP Use of a Gene Expression Test (Corus CAD or ASGES) in Coronary Artery Disease Diagnosis https://ClinicalTrials.gov/show/NCT01594411 Completed CardioDx 2013-01-31
NCT01557855 Investigation of a Novel Gene Expression Test (ASGES or Corus CAD) for Diagnosis of Obstructive Coronary Artery Disease https://ClinicalTrials.gov/show/NCT01557855 Completed CardioDx 2013-03-31
NCT01486030 Effect of Exercise Stress Testing on Peripheral Gene Expression Using Corus CAD (or ASGES) Diagnostic Test https://ClinicalTrials.gov/show/NCT01486030 Completed CardioDx 2013-11-30
NCT01387152 Prognosis of Very Low Dose SPECT https://ClinicalTrials.gov/show/NCT01387152 Completed Columbia University 2012-11-30
NCT01379131 Previous Cardiovascular Disease, Cardiovascular Risk Factors and Chest Pain in First Myocardial Infarction https://ClinicalTrials.gov/show/NCT01379131 Completed London School of Hygiene and Tropical Medicine 2013-12-31
NCT01377402 ARgentinean Risk Assessment Registry in ACS; the ARRA-RACS Study https://ClinicalTrials.gov/show/NCT01377402 Completed Helse Stavanger HF 2010-12-31
NCT04410757 Point of Care Ultrasound Evaluation in the Post-Anesthesia Unit https://ClinicalTrials.gov/show/NCT04410757 Completed Loma Linda University 2019-08-01
NCT04237688 ECG Methods for the Prompt Identification of Coronary Events https://ClinicalTrials.gov/show/NCT04237688 Recruiting University of Pittsburgh 2020-12-31
NCT04226638 Slipping Rib Syndrome: A Clinical Entity to Consider in Chest Pain https://ClinicalTrials.gov/show/NCT04226638 Completed AMS Centro Medico del Ejercicio 2019-11-10
NCT04000490 External Validation of the SCARE Score https://ClinicalTrials.gov/show/NCT04000490 Recruiting Centre Hospitalier Régional d’Orléans 2020-04-01
NCT03913767 Chest Pain Triage at ED https://ClinicalTrials.gov/show/NCT03913767 Recruiting Université Catholique de Louvain 2019-12-31
NCT03731338 Nurse-Led Rapid Access Chest Pain Clinic https://ClinicalTrials.gov/show/NCT03731338 Completed The Royal Wolverhampton Hospitals NHS Trust 2018-12-01
NCT03712020 Investigating the Role of Active Versus Chronic Coronary Artery Calcification on Acute Myocardial Infarct https://ClinicalTrials.gov/show/NCT03712020 Completed National Heart Centre Singapore 2016-03-31
NCT03628586 Biomarkers and Risk Scores for Risk Stratification of Unstable Angina https://ClinicalTrials.gov/show/NCT03628586 Active, not recruiting Liverpool University Hospitals NHS Foundation Trust 2018-10-01
NCT03561051 The Pre-hospital Evaluation of Sensitive Troponin (PRESTO) Study https://ClinicalTrials.gov/show/NCT03561051 Recruiting Manchester University NHS Foundation Trust 2020-05-31
NCT03548753 Use of FFR-CT in Stable Intermediate Chest Pain Patients With Severe Coronary Calcium Score https://ClinicalTrials.gov/show/NCT03548753 Completed Odense University Hospital 2018-04-30
NCT03511430 “SVEAT” Chest Pain Scoring System https://ClinicalTrials.gov/show/NCT03511430 Completed University of Nevada, Reno 2018-09-15
NCT03421873 Effectiveness and Safety of a Clinical Assessment and 0h/1h Troponin Rule-Out Protocol https://ClinicalTrials.gov/show/NCT03421873 Completed Region Skane 2018-12-30
NCT01251302 Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern https://ClinicalTrials.gov/show/NCT01251302 Completed CardioDx 2012-02-29
NCT01236157 Monitoring of Nontraumatic Chest Pain Borne by the “Department of Emergency Help Medicalized” (SAMU) https://ClinicalTrials.gov/show/NCT01236157 Completed French Cardiology Society 2011-11-30
NCT01197716 German Chest Pain Unit (CPU)-Register https://ClinicalTrials.gov/show/NCT01197716 Completed Stiftung Institut fuer Herzinfarktforschung 2015-12-31
NCT01185899 Usefulness of High-frequency QRS Analysis in the Evaluation of Patients With Chest Pain https://ClinicalTrials.gov/show/NCT01185899 Completed Soroka University Medical Center 2013-08-31
NCT01163019 2D Strain Echocardiography for Diagnosing Chest Pain in the Emergency Room https://ClinicalTrials.gov/show/NCT01163019 Completed Technion, Israel Institute of Technology 2014-02-28
NCT01137513 T-Wave Alternans in Patients With Suspected Acute Coronary Syndrome https://ClinicalTrials.gov/show/NCT01137513 Completed Loma Linda University 2013-12-31
NCT01117506 Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES) https://ClinicalTrials.gov/show/NCT01117506 Completed CardioDx 2011-05-31
NCT00922662 Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE) https://ClinicalTrials.gov/show/NCT00922662 Completed William Beaumont Hospitals 2016-09-30
NCT00855231 Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain https://ClinicalTrials.gov/show/NCT00855231 Completed University of Washington 2009-07-31
NCT03800862 The Evaluation of the Roles of New Cardiac Imaging in Patients With Chest Pain https://ClinicalTrials.gov/show/NCT03800862 Recruiting Lancaster General Hospital 2021-01-03
NCT02116426 Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome https://ClinicalTrials.gov/show/NCT02116426 Completed Centre Hospitalier Universitaire de NÄ«mes 2017-08-01
NCT00713102 Surgical and Medical Emergencies on Board of European Aircraft Carriers https://ClinicalTrials.gov/show/NCT00713102 Completed Ruhr University of Bochum 2008-08-31
NCT00657436 Myeloid-Related Protein in Evaluation of Acute Chest Pain in the Emergency Departement https://ClinicalTrials.gov/show/NCT00657436 Completed University of Zurich 2010-12-31
NCT00640068 Advanced Cardiovascular Imaging Consortium https://ClinicalTrials.gov/show/NCT00640068 Completed William Beaumont Hospitals 2014-04-30
NCT00521976 Risk Markers in the Acute Coronary Syndromes https://ClinicalTrials.gov/show/NCT00521976 Completed Helse Stavanger HF 2005-12-31
NCT00500617 Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree https://ClinicalTrials.gov/show/NCT00500617 Completed CardioDx 2010-01-31
NCT00481468 Validation of the Siemens System Somatom Definition and Operating Software for Cardiac CT Studies https://ClinicalTrials.gov/show/NCT00481468 Completed William Beaumont Hospitals 2007-06-30
NCT00380094 Triage Now: an Observational, Prospective Multimarker Study of Biomarkers in Patients Presenting With Chest Pain https://ClinicalTrials.gov/show/NCT00380094 Completed Biosite NA
NCT00373828 Non-cardiac Chest Pain Evaluation and Treatment Study (CARPA) - Part 1: Diagnosis. https://ClinicalTrials.gov/show/NCT00373828 Completed Clinical Locomotion Science 2008-03-31
NCT00328315 Cardiac SPECT With Rotating Slant Hole Collimator https://ClinicalTrials.gov/show/NCT00328315 Completed Johns Hopkins University 2007-12-31
NCT00256581 Imaging Studies With GE C-Hawk Gamma Camera Compared to Routine Clinical Exam https://ClinicalTrials.gov/show/NCT00256581 Completed University of Wisconsin, Madison 2007-06-30
NCT00219492 Role of Esophageal Mast Cell Activation in Noncardiac Chest Pain (NCCP) https://ClinicalTrials.gov/show/NCT00219492 Completed Milton S. Hershey Medical Center 2014-08-21
NCT00187954 WISE ARIC: Retinal Photography in Women With Chest Pain https://ClinicalTrials.gov/show/NCT00187954 Completed University of Florida 2014-09-30
NCT00166231 Understanding Pediatric Chest Pain and Other Symptoms https://ClinicalTrials.gov/show/NCT00166231 Completed Emory University 2009-12-31
NCT00669968 Study of Value of Cardiac PET Scans With or Without CT Angiography and/or Measurement of Coronary Flow Reserve https://ClinicalTrials.gov/show/NCT00669968 Completed Kettering Health Network 2011-05-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03091829 Chest Pain Unit II Register https://ClinicalTrials.gov/show/NCT03091829 Active, not recruiting Stiftung Institut fuer Herzinfarktforschung 2018-04-30
NCT02753023 Registry Of Acute meDical Emergencies in Brazil https://ClinicalTrials.gov/show/NCT02753023 Recruiting University of Sao Paulo General Hospital 2019-01-31
NCT02536677 The Evaluation and Management of Patients With Acute ChesT Pain in China https://ClinicalTrials.gov/show/NCT02536677 Completed Qilu Hospital of Shandong University 2017-10-31
NCT02355457 Biomarkers in Acute Cardiac Care https://ClinicalTrials.gov/show/NCT02355457 Recruiting Universitätsklinikum Hamburg-Eppendorf 2021-12-31
NCT01799655 Does Vitamin D Deficiency Associated With Hypercoagulability & Increased Thrombin Generation? https://ClinicalTrials.gov/show/NCT01799655 Completed HaEmek Medical Center, Israel 2014-04-30
NCT04122573 Prospective Multicenter Study for Early Evaluation of Acute Chest Pain https://ClinicalTrials.gov/show/NCT04122573 Recruiting West China Hospital 2021-10-31
NCT03634384 Rapid Use of High-sensitive Cardiac Troponin I for ruling-in and Ruling-out of Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT03634384 Recruiting University of Aarhus 2019-03-01
NCT03619733 Modified HEART as Rule Out for Suspected ACS https://ClinicalTrials.gov/show/NCT03619733 Recruiting Liverpool University Hospitals NHS Foundation Trust 2018-09-01
NCT03494556 Prehospital Translation of Chest Pain Tools https://ClinicalTrials.gov/show/NCT03494556 Completed Wake Forest University Health Sciences 2019-02-18
NCT03439449 Computerized Medical History Taking for Acute Chest Pain https://ClinicalTrials.gov/show/NCT03439449 Recruiting Karolinska Institutet 2021-12-31
NCT03111862 Safety of Accelerated Rule-out Protocols in Patients Admitted With Chest Pain to a Crowded Chest Pain Unit (CPU) https://ClinicalTrials.gov/show/NCT03111862 Completed University Hospital Heidelberg 2018-08-01